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Agifix-50 Dry Syrup

  • Categeory : Agifix

MRP : 44.30

Available : In-Stocks

Cefixime 50 mg for Oral Suspension

Composition

Each 5 ml of reconstituted AGIFIX Dry Syrup contains:
Cefixime trihydrate Equivalent to anhydrous cefixime … 50 mg

Therapeutic Indications & Usage

AGIFIX-50 (Cefixime 50 mg) Dry Syrup from Agex Laboratories is indicated for the treatment of infections caused by susceptible bacteria:
• Upper respiratory tract infections, such as pharyngitis, sinusitis, otitis media, tonsillitis.
• Lower respiratory tract infections, such as acute bronchitis and acute exacerbation of chronic bronchitis.
• Uncomplicated urinary tract infections.
• Uncomplicated gonorrhea.

Contraindications

AGIFIX-50 (Cefixime-50 mg) Dry Syrup is not advocated for those with a history of hypersensitivity to beta-lactams, e.g. penicillins and cephalosporins.

Precautions & Warnings

AGIFIX-50 (Cefixime-50 mg) Dry Syrup should be advocated with caution in presence of renal impairment or GI disease, particularly colitis. Prolonged use of AGIFIX-50 could result in overgrowth of non-susceptible organisms. If superinfections occur (usually involving Aerobacter, Pseudomonas or Candida spp), AGIFIX-50 should be discontinued and/or appropriate therapy instituted.

Periodic assessment of hematopoietic function is advisable during prolonged AGIFIX therapy. Safety and efficacy of cefixime in children less than 6 months old have not been established.

AGIFIX-50 (Cefixime 50 mg) Dry Syrup must be coadministered with carbamazepine, warfarin and other anticoagulants.

Adverse Reactions

The most frequent adverse effect is gastrointestinal (GI) complaints, and diarrhea incidence is 16%. Other side effects include hypersensitivity reactions, liver / renal dysfunction, headaches, dizziness, seizures, hematopoietic changes, genital pruritus, vaginitis, candidiasis.

Drug Interaction

Elevated carbamazepine levels occur when cefixime AGIFIX is coadministered. When given with warfarin / anticoagulants, the prothrombin time is elevated. Probenecid can decrease its clearance, whilst cholestyramine diminishes absorption of paracetamol when coadministered.

Recommended Dosage & Administration

Children
<50 kg: 8 mg/kg/day of AGIFIX Suspension / AGIFIX 50 / 100 DT either as single dose or in two divided doses. >50 kg:

Presentation
AGIFIX 50: 30 ml bottle with measuring cap