Indications

• URTIs & LRTIs
• UTIs
• SSTIs
• Typhoid Fever

Contraindications
Cefpodoxime is contraindicated to the patient with hypersensitivity with cephalosporin.

Precautions & Warnings
Before therapy AGEXTIL (Cefpodoxime) from Agex Laboratories is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporin, penicillins.
AGEXTIL (Cefpodoxime) is broad-spectrum antibiotics and should be prescribed with caution in individuals with a history of colitis. AGEXTIL should be used in pregnant women and nursing mother only if needed, because safety has not been clearly established.

Adverse Reaction
AGEXTIL-200 Tablets may cause side effects like diarrhea, nausea, vaginal infections, headache, abdominal pain, mild skin rashes, hives, chest pain, and irregular heart beat.

Drug Interactions
Carbamazepine: Elevated carbamazepine levels have been reported when cefpodoxime is administered concomitantly.

Warfarin and Anticoagulants: Increased prothrombin time, with or without clinical bleeding, has been reported when cefpodoxime is administered concomitantly.

Oral Contraceptives: cefpodoxime may interfere with the effectiveness of birth control pills

Dosage

Adults

Bronchitis: Acute bacterial exacerbation of chronic bronchitis: 200 mg orally every 12 hours for 10 days Cystitis: 100 mg orally every 12 hours for 7 days Gonococcal Infection – Uncomplicated: Uncomplicated urethral, cervical, or female anorectal infections: 200 mg orally one time Gonococcal Infection – Disseminated: 400 mg orally twice a day Community-acquired pneumonia: 200 mg orally every 12 hours for 14 days Pyelonephritis: 100 mg orally every 12 hours. Therapy should be continued for about 14 days, depending on the nature and severity of the infection. Sinusitis: 200 mg orally every 12 hours for 10 days Skin or Soft Tissue Infection: Uncomplicated infection: 400 mg orally every 12 hours for 7 to 14 days Tonsillitis/Pharyngitis: 100 mg orally every 12 hours for 5 to 10 days There are insufficient data to establish efficacy in the subsequent prophylaxis of rheumatic fever. Upper Respiratory Tract Infection: 100 mg orally every 12 hours. Therapy should be continued for approximately 10 to 14 days, depending on the nature and severity of the infection.

Presentations
AGEXTIL-200: Alu Alu of 10s