Indications

• URTIs & LRTIs
• UTIs
• SSTIs
• Typhoid Fever

Contraindications
Cefpodoxime is contraindicated to the patient with hypersensitivity with cephalosporin.

Precautions & Warnings
Before therapy AGEXTIL-50 (Cefpodoxime 50 mg) Dry Syrup is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporin, penicillins.
AGEXTIL (Cefpodoxime) is broad-spectrum antibiotics and should be prescribed with caution in individuals with a history of colitis.

Adverse Reaction
AGEXTIL-50 (Cefpodoxime 50 mg) Dry Syrup may cause side effects like diarrhea, nausea, vaginal infections, headache, abdominal pain, mild skin rashes, hives, chest pain, and irregular heart beat.

Drug Interactions

• Carbamazepine: Elevated carbamazepine levels have been reported when cefpodoxime is administered concomitantly.
• Warfarin and Anticoagulants: Increased prothrombin time, with or without clinical bleeding, has been reported when cefpodoxime is administered concomitantly.

Dosage

Children Bronchitis: Acute bacterial exacerbation of chronic bronchitis: 12 years or older: 200 mg orally every 12 hours for 10 days.

Cystitis: 12 years or older: 100 mg orally every 12 hours for 7 days

Gonococcal Infection – Uncomplicated: Uncomplicated urethral, cervical, or female anorectal infections: 12 years or older: 200 mg orally one time

Gonococcal Infection – Disseminated: 12 years or older: 400 mg orally twice a day

Otitis Media: 2 months through 12 years: 5 mg/kg/dose (maximum 200 mg) orally every 12 hours for 5 days; Maximum dose: 400 mg/day

Community-acquired pneumonia: 12 years or older: 200 mg orally every 12 hours for 14 days

Sinusitis: 2 months through 12 years: 5 mg/kg/dose (maximum 200 mg) orally every 12 hours for 10 days. Maximum dose: 400 mg/day. 12 years or older: 200 mg orally every 12 hours for 10 days

Uncomplicated Skin or Soft Tissue Infection: 12 years or older: 400 mg orally every 12 hours for 7 to 14 days

Tonsillitis/Pharyngitis: 2 months through 12 years: 5 mg/kg/dose (maximum 100 mg) orally every 12 hours for 5 to 10 days. Maximum dose: 200 mg/day. 12 years or older: 100 mg orally every 12 hours for 5 to 10 days.

Presentations
AGEXTIL-50: Bottle of 30 ml with measuring cap