Indications
Severe Malaria
             
Contraindications
Artex-60 Injection is contraindicated to hypersensitivity for Artesunate.
            
Precautions & Warnings
Special Precautions in Hepatic or renal insufficiency. Pregnancy and lactation.
             
Adverse Reactions
Adverse Drug Reactions with Artex-60 (Artesunate 60 mg) Injection are Transient and reversible reticulocytopaenia, drug fever, rash, bradycardia, transient 1st-degree heart block and reversible elevation of serum transaminases. 
             
Drug Interaction
Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline.
Additive effect with chloroquine. Antagonistic effect with pyrimethamine and sulphonamides.
             
Dosage
Adult: 2.4 mg/kg via IM or IV admin. Repeat 12 hr and 24 hr later, then once daily thereafter.
         
Child: 2.4 mg/kg via IM or IV admin. Repeat 12 hr and 24 hr later, then once daily thereafter
             
Presentations
Artex-60: VIAL + Sodium Bicarbonate Injection + WFI