MRP : 135
Indications
Uncomplicated P. falciparum malaria
Resistant P. vivax infections
Mixed, alarial infections
Contraindications
Hypersensitivity to artemether, lumefantrine, or any ingredient in the formulations.
Precautions & Warnings
QT interval prolongation reported.
Do not use in patients with congenital long QT syndrome, clinical conditions known to prolong the QTc interval (e.g., symptomatic cardiac arrhythmias, clinically important bradycardia, severe cardiac disease), family history of congenital long QT syndrome or sudden death, or in those with electrolyte abnormalities (e.g., hypokalemia, hypomagnesemia)
Do not use in those receiving treatment with class IA or III antiarrhythmic agents, antipsychotics (e.g., pimozide, ziprasidone), antidepressants, certain anti-infectives (e.g., macrolides, fluoroquinolones, imidazole- or triazole-derivative antifungal agents), cisapride (available in the US only under a limited-use protocol), or drugs known to be CYP2D6 substrates with cardiac effects
Drug Interaction
Concomitant use with certain drugs requires particular caution (e.g., other antimalarial drugs, antiretroviral agents).
Dosage
As prescribed by the physician
Presentation
Agither-L Dry Syrup: 30 mL bottle with sterile water