Indications
Sofril-40 (Isoxspuprine HCL 40mg) Tablet is used to improve blood flow in: 
• Cerebral vascular insufficiency Arteriosclerosis obliterans 
• Buerger disease 
• Raynaud disease 

Contraindications
Except under special circumstances, Sofril-40 (Isoxsuprine 40mg) tablet should not be used immediately postpartum or when the following medical problems exist:
For use in management of premature labor only:
• Cardiac disorders, especially those associated with arrhythmias, or
• Hyperthyroidism, maternal    
• Chorioamnionitis (intrauterine infection) 
• Hemorrhage 
• Intrauterine fetal death or known abnormality
• Eclampsia (toxemia) and severe pre-eclampsia
• Pulmonary hypertension

Precautions & Warnings 
Sofril-40 (Isoxsuprine 40 mg) tablets may cause dizziness, therefore driving or operating heavy machinery during the drug administration is not prohibited. 

It is unknown if isoxsuprine is excreted in breast milk. 

Adverse Reactions 
Signs of potential side effects, especially allergic reaction, chest pain, pulmonary edema, hypotension, and tachycardia. 

Dosage & Administration
Sofril-40: Three times a day. 

Presentation
Sofril-40: Blister of 10s